DACTOVIN

Dactovin-12weeks-Daclatasvir-Tablets-60mg


DACTOVIN

BRAND : DACTOVIN
STRENGTH :60 MG
COMPANY NAME :STRIDES
TABLETS : 28 TABLETS

DESCRIPTION

DACTOVIN ( DACLATASVIR)IS A NS5A REPLICATION COMPLEX INHIBITOR. Dactovin ( Daclatasvir)is specifically indicated for use with sofosbuvir for the treatment of patients with chronic hepatitis C virus (HCV) of genotype 1, 3, or 4 infections. The other medications used in combination include sofosbuvir, ribavirin, and interferon, vary depending on the virus type and whether the person has cirrhosis. Dactovin ( Daclatasvir) stops HCV viral RNA replication and protein translation by directly inhibiting HCV protein NS5A. NS5A is critical for HCV viral transcription and translation, Dactovin ( Daclatasvir)is supplied as tablets for oral administration. It is taken by mouth once a day. The recommended dose is 60 mg taken orally once daily with or without food in combination with sofosbuvir.

The recommended treatment duration is 12 weeks. Dose modification: reduce dosage to 30 mg once daily with strong CYP3A inhibitors and increase dosage to 90 mg once daily with moderate CYP3A inducers.

Concomitant use of drugs that are strong inducers of the cytochrome P450 CYP3A is contraindicated due to decreased therapeutic effect and resistance of drug. Some common drugs that are strong CYP3A inducers include dexamethasone, phenytoin, carbamazepine, rifampin and St. John's Wort. Dactovin ( Daclatasvir) is a CYP3A and p-glycoprotein substrate, therefore, drugs that are strong inducers or inhibitors of these enzyme will interfere with daclatascir levels in the body.

Dose modifications are made with concomitant use of daclatasvir and drugs that affect CYP3A or p-gp. When taking daclatasvir with non-nucleoside reverse transcriptase inhibitors, the dose of daclatasvir is increased to overcome CYP3A induction. The dose for daclatasvir should be lowered when taking with antifungals, such as ketoconazole. Currently, there are no required dosage adjustments with concurrent use of daclatasvir and immunosuppressants, narcotic analgesics, antidepressants, sedatives, and cardiovascular agents. Concurrent use with amiodarone, sofosbuvir and daclatasvir has may result in an increased risk for serious slowing of the heart rate.

Common side effects with sofosubvir and daclatasvir include headache, feeling tired, and nausea. With daclatasvir, sofusbivir, and ribavirin the most common side effects are headache, feeling tired, nausea, and red blood cell breakdown.

It should not be used with St. John's wort, rifampin, or carbamazepine. It works by inhibiting the HCV protein NS5A. It is on the World Health Organization's List of Essential Medicines.

Call To Million health pharmaceuticals

Million health pharmaceuticals has an established history of contract manufacturing Tablets, Capsules,Injections .Ointments,Syrups,Dry Syrups etc, of sterile formulations for the various pharmaceutical and biotechnology companies. From large organizations to small, Million health pharmaceuticals can accommodate a wide range of manufacturing needs.

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Million Health Pharmaceuticals

Million Health Pharmaceuticals can produce sterile products in vial sizes ranging from 1ml to 100ml. Million health pharmaceuticals can also produce sterile formulations in prefilled syringes, bags, or bottle format.

Portion 'A' First Floor,
Old No. 131, New No. 50,
Pedariyar Koil Street,
Seven Wells,
Chennai - 600001.
Tamilnadu,India

+91-9940472902

millionhealthpharmaceuticals@gmail.com

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DISCLAIMER

This information should not be used to decide whether or not to take this Product or any other medicine. Only the healthcare provider has the knowledge and training to decide which medicines are right for a specific patient. This information does not endorse any medicine as safe, effective, or approved for treating any patient or health condition. This is only a brief summary of general information about this Product . It does NOT include all information about the possible uses, directions, warnings, precautions, interactions, adverse effects, or risks that may apply to this product. This information is not specific medical advice and does not replace information you receive from the healthcare provider. You must talk with the healthcare provider for complete information about the risks and benefits of using this product.