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DACLATASVIR

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Daclatasvir dihyhrochloride

Daclatasvir dihyhrochloride is available as a tablet form which contains anti viral activity that prohibits the NS5A domain of the hepatitis C virus (HCV) Generally it is used in combinational therapy, with other anti viral agents to cure chronic hepatitis C.

Mechanism of action :

Daclatasvir act as hepatitis C NS5A inhibitor. It is also a P-Glycoprotein Inhibitor, organic anion transporting polypeptide 1B1, 1B3 inhibitor and breast cancer resistance protein inhibitor. It worked by blocking the viral replication leads to chain termination.

Side effects :

• Chest pain or discomfort
• lightheadedness, dizziness, or fainting
• slow or irregular heartbeat
• unusual tiredness

More common :

• Headache
• nausea

Less common :

• Diarrhea

Nervous system :

• Headache
• Dizziness
• migraine
• somnolence

Dermatologic :

• Headache
• Erythema
• Pruritus
• rash, dry skin
• alopecia
• Erythema multiforme

Psychiatric :

• Insomnia
• irritability
• Depression
• anxiety

Hematologic :

• Anemia
• neutropenia
• Thrombocytopenia
• decreased hemoglobin
• Headache
• Eosinophilia


Respiratory :

• Cough, Nasopharyngitis
• dyspnea, Exertional dyspnea
• nasal congestion
• upper respiratory tract infection

Gastrointestinal :

• Diarrhea,nausea
• Upper abdominal pain
• abdominal pain
• constipation, flatulence
• gastro esophageal reflux disease
• dry mouth, vomiting,
• elevated lipase

Musculoskeletal :

• Myalgia
• arthralgia
• Back pain

Metabolic :

• Decreased appetite

Cardiovascular :

• Symptomatic bradycardia
• heart block
• cardiac arrhythmias

Hepatic :

• Increased ALT
• increased AST
• increased total bilirubin
• Hepatitis B reactivation

Genitourinary :

• Urinary tract infection

Ocular :

• Dry eye



Dosage and administration :

Daclatasvir not used alone, it is combined with Sofosbuvir.

Genotype I :

Without cirrhosis and compensated cirrhosis: Daclatasvir with Sofosbuvir for 12 weeks Decompensated cirrhosis: Daclatasvir with Sofosbuvir combined with ribavirin for 12 weeks.

Genotype III :

Without cirrhosis: Daclatasvir with Sofosbuvir for 12 weeks Compensated or decompensated cirrhosis: Daclatasvir with Sofosbuvir combined with ribavirin for 12 weeks.

Precaution :

It should not use alone; it must be combined with Sofosbuvir.

Storage :

It should be store at room temperature, 68°F to 77°F (20°C to 25°C).

Product Features

daclatasvir-features 1

daclatasvir-features 2

DACLAHEP

BRAND : DACLAHEP
STRENGTH : DACLATASVIR 60 MG
COMPANY NAME : HETERO
TABLETS : 28

MYDEKLA

BRAND : MYDEKLA
STRENGTH : DACLATASVIR 60 MG
COMPANY NAME : MYLAN
TABLETS : 28

NATDAC

BRAND : NATDAC
STRENGTH : DACLATASVIR 60 MG
COMPANY NAME : NATCO
TABLETS : 28

DACTOVIN

BRAND : DACTOVIN
STRENGTH : DACLATASVIR 60 MG
COMPANY NAME : STRIDES
TABLETS : 28

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Call To Million health pharmaceuticals

Million health pharmaceuticals has an established history of contract manufacturing Tablets, Capsules,Injections .Ointments,Syrups,Dry Syrups etc, of sterile formulations for the various pharmaceutical and biotechnology companies. From large organizations to small, Million health pharmaceuticals can accommodate a wide range of manufacturing needs.

Million Health Pharmaceuticals

Million Health Pharmaceuticals can produce sterile products in vial sizes ranging from 1ml to 100ml. Million health pharmaceuticals can also produce sterile formulations in prefilled syringes, bags, or bottle format.

Portion 'A' First Floor,
Old No. 131, New No. 50,
Pedariyar Koil Street,
Seven Wells,
Chennai - 600001.
Tamilnadu,India

+91-9940472902

millionhealthpharmaceuticals@gmail.com

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DISCLAIMER

This information should not be used to decide whether or not to take this Product or any other medicine. Only the healthcare provider has the knowledge and training to decide which medicines are right for a specific patient. This information does not endorse any medicine as safe, effective, or approved for treating any patient or health condition. This is only a brief summary of general information about this Product . It does NOT include all information about the possible uses, directions, warnings, precautions, interactions, adverse effects, or risks that may apply to this product. This information is not specific medical advice and does not replace information you receive from the healthcare provider. You must talk with the healthcare provider for complete information about the risks and benefits of using this product.